Drug-Induced Diabetes Mellitus.

Yi,  Dongwon; Kang,  Yang Ho

doi:2017.18.3.160

J Korean Diabetes > Volume 18(3); 2017 > Article

Focused Issue

The Journal of Korean Diabetes 2017;18(3):160-168.
DOI: https://doi.org/10.4093/jkd.2017.18.3.160 Published online October 12, 2017.

약제와 관련된 당뇨병

이동원, 강양호

Drug-Induced Diabetes Mellitus.

Dongwon Yi, Yang Ho Kang

Division of Endocrinology and Metabolism, Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea. kangyh@pusan.ac.kr

Abstract

Drug-induced diabetes is becoming more prevalent as a result of individuals taking diverse types of medication. A variety of drugs can impair glucose tolerance through several mechanisms, including increased insulin resistance, diminished insulin secretion, or both. Efforts should be made to identify and closely monitor patients receiving drugs that may alter glucose metabolism as diabetes is a leading cause of morbidity and mortality. We review the latest data concerning commonly used drugs associated with development of diabetes and present postulated mechanisms by which the drugs might cause diabetes.

Key Words: Diabetes mellitus, Drug-related side effects and adverse reactions, Hyperglycemia, Metabolic side effects of drugs and substances