Metabolic Surgery and Diabetes Mellitus: Its Effects and Side Effects.

Kim,  Mee Kyoung

doi:2019.20.4.205

J Korean Diabetes > Volume 20(4); 2019 > Article

Opinion

The Journal of Korean Diabetes 2019;20(4):205-209.
DOI: https://doi.org/10.4093/jkd.2019.20.4.205 Published online January 17, 2020.

비만대사수술과 당뇨병: 그 효과와 부작용

김미경

Metabolic Surgery and Diabetes Mellitus: Its Effects and Side Effects.

Mee Kyoung Kim

Division of Endocrinology and Metabolism, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. makung@catholic.ac.kr

Abstract

Recent studies have shown that metabolic surgery can lead to the remission of diabetes mellitus (DM) in a large portion of patients with both type 2 DM and morbid obesity. Metabolic surgery may be considered for glycemic control and weight loss in obese patients with type 2 DM. The most commonly performed bariatric surgeries are sleeve gastrectomy and Roux-en-Y gastric bypass. The effect of metabolic surgery, especially Roux-en-Y gastric bypass, is thought to be caused by mechanisms other than weight loss. Increased insulin secretion associated with altered gut hormones might play a role in this improvement. After metabolic surgery, glucose, lipids, and blood pressure are greatly improved, but not all patients with type 2 DM who undergo metabolic surgery achieve DM remission.

Key Words: Bariatric surgery, Diabetes mellitus, Korea