A Case of Fulminant Type 1 Diabetes with Diabetic Ketoacidosis and Acute Renal Failure

Lim, Chae Young; Kim, Hyo Jeong; Min, Kyung Wan; Kim, Hyun Jin; Park, Kang Seo; Kim, Eung Jin; Han, Kyung Ah

Case Report

Clinical Diabetes 2006;7(4):374-377.

당뇨병성 케톤산증과 급성 신부전을 동반한 전격성 당뇨병 1예

임채영, 김효정, 민경완, 김현진, 박강서, 김응진, 한경아

A Case of Fulminant Type 1 Diabetes with Diabetic Ketoacidosis and Acute Renal Failure

Chae Young Lim, Hyo Jeong Kim, Kyung Wan Min, Hyun Jin Kim, Kang Seo Park, Eung Jin Kim, Kyung Ah Han

Abstract

Type 1 diabetes mellitus results from insulin deficiency due to destructive process of the beta cells. Type 1 diabetes mellitus is divided into autoimmune-mediated (type 1A) and idiopathic (type 1B). Since Imagawa et al. reported 11 cases of fulminant autoantibody-negative type 1 diabetes as a novel subtype, additional cases were described. Most of type 1B diabetes were characterized by abrupt and severe onset of disease, negative status of islet-related autoantibodies, elevated serum pancreatic enzyme, and a near-normal range of HbA1c. We have assessed the 32-year old man who had fulminant diabetes associated with diabetic ketoacidosis and acute renal failure, and so report the case with the review of literatures.

Key Words: Fulminant, Type 1B diabetes, ketoacidosis