| 관상동맥질환에서의 당뇨병 환자의 임상적 고찰 |
|
이병완, 강보현, 강한욱, 김형훈, 김현진, 노정현, 지재환, 하창영, 정재훈, 민용기, 이명식, 이문규, 김광원 |
|
|
| Clinical and Angiographic Review of Diabetes Mellitus in Coronary Artery Disease |
|
Byung W Lee, Bo H Kang, Hahn W Kang, Hyung H Kim, Hyun J Kim, Jung H Noh, Jae H Jee, Chang Y Ha, Jae H Chung, Young K Min, Myung S Lee, Moon K Lee, Kwang W Kim |
|
|
| Abstract |
Background
Diabetes is a very important risk factor of coronary artery disease. The prevalence of diabetes in Korea is increasing steadily. The objective of this study was to establish the prevalence and cardiovascular risk factors of diabetes in coronary artery disease in Korean type 2 diabetes. Methods: Of the patients enrolled in SMC-coronary artery angiography protocol, we investigated 1143 subjects (from Jan. 1st to Dec.31th, 2001) with suspicious coronary artery disease reflected from symptoms of chest pain, EKG and enzyme abnormalities, and thallium scan. Sociodemographic characteristics and laboratory data were investigated using retrospective analysis. Results: The prevalence of diabetes in coronary artery disease patients was 37.49 %. The risk factors of coronary artery disease were diabetes, old age, obesity, hypertension, smoking and family history of coronary artery disease in our study. Among patients with coronary artery disease, there were significant differences in age, hypertension, smoking, family history of coronary artery disease, and levels of HDL-C, triglyceride, fibrinogen, t-PA, PAI-1 between diabetic patients and normo-glycemic patients. In the comparison of patients with myocardial infarction, there were significant difference in smoking, prescription of lipid-lowering drugs, homocysteine, tPA, PAI-I, and CRP between diabetic patients and normo-glycemic patients. Only the levels of uric acid and HDL-C showed meaningful difference between diabetic patients with well-controlled blood sugar and poorly-controlled blood sugar. Conclusion: With the increase in the prevalence of diabetes, the proportion of diabetic patients in coronary artery disease has also increased. Among patients with coronary artery disease, the risk factors of coronary artery disease were age, hypertension, smoking, family history of coronary artery disease, and levels of HDL-C, triglyceride, fibrinogen, t-PA, PAI-1 in diabetic patients compared to normo-glycemic patients. Diabetic patients must stop smoking and maintain strict control of blood pressure and blood glucose level. In addition, HDL-C was very important predictive risk factor for coronary artery disease. |
| Key Words:
Diabetes, Coronary artery disease, HDL-C |
|
PDF Links
Full text via DOI
Download Citation
