J Korean Diabetes > Volume 20(1); 2019 > Article
The Journal of Korean Diabetes 2019;20(1):1-5.
DOI: https://doi.org/10.4093/jkd.2019.20.1.1    Published online April 4, 2019.
심부전: 2형 당뇨병의 합병증
설상훈
Heart Failure: Complications of Type 2 Diabetes.
Sang Hoon Seol
Division of Cardiology, Department of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea. hacemed@hanmail.net
Abstract
There is a close relationship between diabetes mellitus and heart failure, both of which are known to increase morbidity and mortality. Diabetes can cause or aggravate heart failure, and heart failure can precipitate diabetes. Diabetes mellitus causes structural and functional changes in the heart, such as fibrosis of the myocardium and left ventricular dysfunction. The mechanisms of diabetic cardiomyopathy are metabolic disturbance, myocardial fibrosis, microvascular disease, and autonomic dysfunction. Improper blood glucose control leads to deterioration of heart failure, but the role of strict glycemic control in reducing heart failure is unclear. The role of SGLT2 inhibitors in reducing the incidence of heart failure is of great importance in the treatment of diabetic patients. However, further long-term follow-up and safety studies are needed.
Key Words: Diabetes complication, Heart failure


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