Antimicrobial Therapy in Diabetic Foot Infections.

Song,  Joon Young

doi:2011.12.2.83

J Korean Diabetes > Volume 12(2); 2011 > Article

Focused Issue

The Journal of Korean Diabetes 2011;12(2):83-87.
DOI: https://doi.org/10.4093/kcd.2011.12.2.83 Published online June 1, 2011.

당뇨병성 족부 감염의 약물치료

송준영

Antimicrobial Therapy in Diabetic Foot Infections.

Joon Young Song

Division of Infectious Disease, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. infection@medimail.co.kr

Abstract

Treatment of diabetic foot infection remains a challenging issue to be solved. Bacterial species complicating diabetic foot ulcer differ from those of non-diabetic patients. Empirical antibiotic regimens are selected based on the severity and type of infection (acute infection versus chronic infection), which should always include coverage for aerobic Gram-positive cocci, especially Staphylococcus aureus. Narrow-spectrum antibiotic agents are considered for mild-to-moderate, recent infections, while broad-spectrum agents are usually required for severe, chronic infections, targeting both Gram-positive cocci and Gram-negative bacilli.

Key Words: Diabetes, Foot infection, Antimicrobial agent, Empirical therapy